Committee Composition Independent Director Audit Committee Human Capital Management & Compensation Committee Nominating & Corporate Governance Committee Research and Development Committee Ellen G. Feigal, M.D. Independent Director Nominating & Corporate Governance Committee Research and Development Committee Kevin C. Gorman, Ph.D. Independent Director Human Capital Management & Compensation Committee Research and Development Committee Kurt A. Gustafson Independent Director Audit Committee Barbara J. Klencke, M.D. Research and Development Committee A. Bruce Montgomery, M.D. Independent Director Audit Committee Human Capital Management & Compensation Committee Research and Development Committee Richard J. Ranieri Independent Director Human Capital Management & Compensation Committee Nominating & Corporate Governance Committee Dagmar Rosa-Bjorkeson Independent Director Audit Committee Nominating & Corporate Governance Committee = Independent Director = Chairperson = Member = Lead Director